4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:基因表达
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > acid_base_buffer_solution > Epigentek/Trichostatin A/M45000-1/1 mg
商品详细Epigentek/Trichostatin A/M45000-1/1 mg
Epigentek/Trichostatin A/M45000-1/1 mg
Epigentek/Trichostatin A/M45000-1/1 mg
商品编号: M45000-1
市场价: ¥4100.00
美元价: 2460.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Application:EnzymeInhibition
MolecularWeight:100-500
ResearchArea:HistoneAcetylation
Solubility:DMSO,Ethanol,Other
100%Guarantee:6months
ProductOverview

AlternativeNames
TSA,[R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptADIenamide

Description
TrichostatinAisapotentandnon-competitivereversIBLeinhibitorofhistonedeacetylases(HDAC)withaKiof3.4nM.InHeLacells,TSAblockedcellcycleprogressionatG1andinduceda12-foldincreaseinintracellularlevelsofgelsolin.IncellslatentlyinfectedwithHIV-1,TSAinducedthetranscriptionalactivationoftheHIV-1promoter,whichresultedinamarkedincreaseinvirusproduction.InNIH3T3cells,TSAinducedreversionofoncogenicras-transformedcellstoanormalmorphology.InJurkatcells,TSAinhibitedIL-2geneexpressionanddisplayedimmunosuppressiveactivityinamousemodel.InducesincreasedacetylationofGATA4,acardiac-specifictranscriptionfactorandincreasescardiacmusclecelldifferentiation.Innormalratfibroblasts,inducedFriendcelldifferentiationandinhibitedtheG1andG2phasesofthecellcycle.TrichostatinAisausefultoolforinductionofhyperacetylationofcellularhistonesandforfurtherelucidationoftheirroleingeneexpression.

CASNumber
58880-19-6

ChemicalFormula
C17H22N2O3

MolecularWeight
302.4

Size
1mg

Purity
99%

Solubility
SolubleinDMSO,DMFandethanol

StorageTemp
-20°C

品牌介绍
Epigentek快速,有效地制备DNA,蛋白质和染色质对于进行下游分析至关重要。我们的样品制备套件套件几乎适用于所有工作流程,无论是为ChIP-Seq或ChIP-PCR应用分离染色质,还是从各种起始原料制备亚硫酸氢盐-Seq或MS-PCR的DNA。我们的样品制备套件使您可以直接从提取到反应,为您的实验工作流程提供无数种可能性和灵活性。我们的DNA,蛋白质和染色质制备试剂盒是无数研究机会和下游应用的起点。