| Application: | EnzymeInhibition |
| MolecularWeight: | 100-500 |
| ResearchArea: | HistoneAcetylation |
| Solubility: | DMSO,Ethanol,Other |
| 100%Guarantee: | 6months |
AlternativeNames
AA,2-Hydroxy-6-pentadecylbenzoicAcid,6-PentadecylsalicylicAcid
Description
AnacardicAcidisapentadecanealiphaticchaincontaininghydroxylcarboxylicacid.Theacidisaneffectiveinhibitoroftheactivitiesofp300andp300/CBPassociatedfactorhistoneacetyltransferase.Additionally,ithasbeenshowntopotentlyinhibitHAT-dependenttranscriptionandSUMOylation,aswellasdecreaseexpressionofNF-κBregulatedgeneproductsincluding,invasion,proliferation,inflammation,andcellsurvival.ResearchsuggeststhatanacardicacidmaybeapotentactivatorofARK-1(AurorakinaseA)mediatedphosphorylationofhistoneH3,andanovelactivatorofAurorakinase.AnacardicAcidhasdemonstratedbactericidalactivityagainstmethicillin-resistantStaphylococcusaureus(MRSA).
CASNumber
16611-84-0
ChemicalFormula
C22H36O3
MolecularWeight
348.52
Size
5mg
Purity
≥95%
Solubility
Solublein100%ethanol,methanol,DMSO,dichloromethaneorethylacetate
StorageTemp
-20°C
