Background
CpG islands are discrete clusters of unmethylated CpG dinucleotides found in the human genome that control gene expression by binding transcription factors. CGBO is a widely expressed binding protein that requires the CpG dinucleotide to bind DNA. CGBP binds strictly to unmethylated CpG motifs and acts as a transcription activator. The CXXC domain of this protein is conserved in DNA methyltransferase, human trithorax, and methyl-CpG binding protein (MBP), and is involved in DNA-binding. CGBO has other domains involved in protein-protein interactions, yet more study is needed to determine the function. 

Concentration
0.2 mg/ml

Description
Rabbit polyclonal antibody to CGBP

Purification
Protein A purified

Specificity
Mouse, rat, human

Isotype
IgG

Formulation
0.1% Sodium Azide, 0.2% Gelatin, PBS

Storage
4°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance

Alternative Names
2410002I16Rik antibody, 5830420C16Rik antibody, AI426635 antibody, CFP 1 antibody, CpG binding protein antibody, CXXC 1 antibody, CXXC finger 1 antibody, CXXC finger 1 PHD domain antibody, CXXC finger protein 1 antibody, CXXC type zinc finger protein 1 antibody, CXXC1 antibody, CXXC1_HUMAN antibody, DNA binding protein with PHD finger and CXXC domain antibody, hCGBP antibody, HsT2645 antibody, PCCX 1 antibody, PHD finger and CXXC domain containing protein 1 antibody, PHF 18 antibody, Protein containing CXXC domain 1 antibody, SPP 1 antibody, ZCGPC 1 antibody, Zinc finger, CpG binding type containing 1 antibody

Application
WB: 1:200-1:500; IF: 1:100-1: 500; ELISA; IP

Fig. 1. WB analysis of CGBP antibody with K-562 cell lysates (A-1013).