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Epigentek/APOBEC3A Polyclonal Antibody/A58106-100/100 µg
| Application: | ELISA |
| Areas of Research: | DNA Methylation |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | >95%, Protein G Purified |
| Reactivity: | Human |
| 100% Guarantee: | 6 months |
Background
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Description
APOBEC3A Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
Specificity
Human
Isotype
IgG
Uniprot ID
P31941
Purification
>95%, Protein G purified
Immunogen
Recombinant human DNA dC->dU-editing enzyme APOBEC-3A protein (1-199AA)
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names
DNA dC->dU-editing enzyme APOBEC-3A (EC:3.5.4.-), A3A, APOBEC3A, Phorbolin-1
Application
ELISA
VCU0006
