
Application: | ELISA |
AreasofResearch: | DNAMethylation |
Clonality: | Polyclonal |
Conjugate: | Unconjugated |
Host: | Rabbit |
Isotype: | IgG |
Purification: | >95%,ProteinGPurified |
Reactivity: | Human |
100%Guarantee: | 6months |
Background
DNAdeaminase(cytidinedeaminase)withrestrictionactivityagainstviruses,foreignDNAandmobilityofretrotransposons.Exhibitsantiviralactivityagainstadeno-associatedvirus(AAV)andhumanT-cellleukemiavirustype1(HTLV-1)andmayinhibitthemobilityofLTRandnon-LTRretrotransposons.Selectivelytargetssingle-strandedDNAandcandeaminatebothmethylcytosineandcytosineinforeignDNA.CaninducesomatichypermutationinthenuclearandmitochondrialDNA.MayalsoplayaroleintheepigeneticregulationofgeneexpressionthroughtheprocessofactiveDNAdemethylation.
Description
APOBEC3APolyclonalAntibody.Unconjugated.Raisedin:Rabbit.
Formulation
Liquid.0.03%Proclin300,50%Glycerol,0.01MPBS,PH7.4.
Specificity
Human
Isotype
IgG
UniprotID
P31941
Purification
>95%,ProteinGpurified
Immunogen
RecombinanthumanDNAdC->dU-editingenzymeAPOBEC-3Aprotein(1-199AA)
Storage
Shippedat4°C.Upondeliveryaliquotandstoreat-20°C(short-term)or-80°C(long-term).Avoidrepeatedfreeze.
AlternativeNames
DNAdC->dU-editingenzymeAPOBEC-3A(EC:3.5.4.-),A3A,APOBEC3A,Phorbolin-1
Application
ELISA
VCU0006