| Application: | ELISA,IF,IHC |
| AreasofResearch: | DNAMethylation |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | >95%,ProteinGPurified |
| Reactivity: | Human |
| 100%Guarantee: | 6months |
Background
DioxygenasethatrepairsalkylatedDNAcontaining1-methyladenine(1meA)and3-methylcytosine(3meC)byoxidativedemethylation.Hasastrongpreferenceforsingle-strandedDNA.Abletoprocessalkylated3mCwithindouble-strandedregionsviaitsinteractionwithASCC3,whichpromotesDNAunwindingtogeneratesingle-strandedsubstrateneededforALKHB3.MayalsoactonRNA.Requiresmolecularoxygen,alpha-ketoglutarateandiron.
Description
ALKBH3PolyclonalAntibody.Unconjugated.Raisedin:Rabbit.
Formulation
Liquid.0.03%Proclin300,50%Glycerol,0.01MPBS,PH7.4.
Specificity
Human
Isotype
IgG
UniprotID
Q96Q83
Purification
>95%,ProteinGpurified
Immunogen
RecombinanthumanAlpha-ketoglutarate-dependentdioxygenasealkBhomolog3protein(1-170AA)
Storage
Shippedat4°C.Upondeliveryaliquotandstoreat-20°C(short-term)or-80°C(long-term).Avoidrepeatedfreeze.
AlternativeNames
AlkylatedDNArepairproteinalkBhomolog3,DEPC-1,Prostatecancerantigen1,ABH3,DEPC1,ALKBH3
Application
ELISA,IHC,IF;Recommendeddilution:IHC:1:20-1:200,IF:1:50-1:200
VCU0006
